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Ethyl pyruvate reduces liver injury at early phase but impairs regeneration at late phase in acetaminophen overdose
INTRODUCTION: Inflammation may critically affect mechanisms of liver injury in acetaminophen (APAP) hepatotoxicity. Kupffer cells (KC) play important roles in inflammation, and KC depletion confers protection at early time points after APAP treatment but can lead to more severe injury at a later tim...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396240/ https://www.ncbi.nlm.nih.gov/pubmed/22248080 http://dx.doi.org/10.1186/cc11149 |