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Galectins as self/non-self recognition receptors in innate and adaptive immunity: an unresolved paradox

Galectins are characterized by their binding affinity for β-galactosides, a unique binding site sequence motif, and wide taxonomic distribution and structural conservation in vertebrates, invertebrates, protista, and fungi. Since their initial description, galectins were considered to bind endogenou...

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Detalles Bibliográficos
Autores principales: Vasta, Gerardo R., Ahmed, Hafiz, Nita-Lazar, Mihai, Banerjee, Aditi, Pasek, Marta, Shridhar, Surekha, Guha, Prasun, Fernández-Robledo, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396283/
https://www.ncbi.nlm.nih.gov/pubmed/22811679
http://dx.doi.org/10.3389/fimmu.2012.00199