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Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells
BACKGROUND: Tumour cells are characterized by aerobic glycolysis, which provides biomass for tumour proliferation and leads to extracellular acidification through efflux of lactate via monocarboxylate transporters (MCTs). Deficient and spasm-prone tumour vasculature causes variable hypoxia, which fa...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396336/ https://www.ncbi.nlm.nih.gov/pubmed/22700320 http://dx.doi.org/10.1007/s13402-012-0081-9 |