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The human phosphotyrosine signaling network: Evolution and hotspots of hijacking in cancer

Phosphotyrosine (pTyr) signaling, which plays a central role in cell–cell and cell–environment interactions, has been considered to be an evolutionary innovation in multicellular metazoans. However, neither the emergence nor the evolution of the human pTyr signaling system is currently understood. T...

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Detalles Bibliográficos
Autores principales: Li, Lei, Tibiche, Chabane, Fu, Cong, Kaneko, Tomonori, Moran, Michael F., Schiller, Martin R., Li, Shawn Shun-Cheng, Wang, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396364/
https://www.ncbi.nlm.nih.gov/pubmed/22194470
http://dx.doi.org/10.1101/gr.128819.111