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Predictive regulatory models in Drosophila melanogaster by integrative inference of transcriptional networks

Gaining insights on gene regulation from large-scale functional data sets is a grand challenge in systems biology. In this article, we develop and apply methods for transcriptional regulatory network inference from diverse functional genomics data sets and demonstrate their value for gene function a...

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Detalles Bibliográficos
Autores principales: Marbach, Daniel, Roy, Sushmita, Ay, Ferhat, Meyer, Patrick E., Candeias, Rogerio, Kahveci, Tamer, Bristow, Christopher A., Kellis, Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396374/
https://www.ncbi.nlm.nih.gov/pubmed/22456606
http://dx.doi.org/10.1101/gr.127191.111