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Comparative dynamic transcriptome analysis (cDTA) reveals mutual feedback between mRNA synthesis and degradation

To monitor eukaryotic mRNA metabolism, we developed comparative dynamic transcriptome analysis (cDTA). cDTA provides absolute rates of mRNA synthesis and decay in Saccharomyces cerevisiae (Sc) cells with the use of Schizosaccharomyces pombe (Sp) as an internal standard. cDTA uses nonperturbing metab...

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Detalles Bibliográficos
Autores principales: Sun, Mai, Schwalb, Björn, Schulz, Daniel, Pirkl, Nicole, Etzold, Stefanie, Larivière, Laurent, Maier, Kerstin C., Seizl, Martin, Tresch, Achim, Cramer, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396375/
https://www.ncbi.nlm.nih.gov/pubmed/22466169
http://dx.doi.org/10.1101/gr.130161.111