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Maximum Diastolic Potential of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Depends Critically on I(Kr)

Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) hold promise for therapeutic applications. To serve these functions, the hiPSC-CM must recapitulate the electrophysiologic properties of native adult cardiomyocytes. This study examines the electrophysiologic characteristics of hi...

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Detalles Bibliográficos
Autores principales: Doss, Michael Xavier, Di Diego, José M., Goodrow, Robert J., Wu, Yuesheng, Cordeiro, Jonathan M., Nesterenko, Vladislav V., Barajas-Martínez, Héctor, Hu, Dan, Urrutia, Janire, Desai, Mayurika, Treat, Jacqueline A., Sachinidis, Agapios, Antzelevitch, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396384/
https://www.ncbi.nlm.nih.gov/pubmed/22815737
http://dx.doi.org/10.1371/journal.pone.0040288