Cargando…
Maximum Diastolic Potential of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Depends Critically on I(Kr)
Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) hold promise for therapeutic applications. To serve these functions, the hiPSC-CM must recapitulate the electrophysiologic properties of native adult cardiomyocytes. This study examines the electrophysiologic characteristics of hi...
Autores principales: | Doss, Michael Xavier, Di Diego, José M., Goodrow, Robert J., Wu, Yuesheng, Cordeiro, Jonathan M., Nesterenko, Vladislav V., Barajas-Martínez, Héctor, Hu, Dan, Urrutia, Janire, Desai, Mayurika, Treat, Jacqueline A., Sachinidis, Agapios, Antzelevitch, Charles |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396384/ https://www.ncbi.nlm.nih.gov/pubmed/22815737 http://dx.doi.org/10.1371/journal.pone.0040288 |
Ejemplares similares
-
Susceptibility to Ventricular Arrhythmias Resulting from Mutations in FKBP1B, PXDNL, and SCN9A Evaluated in hiPSC Cardiomyocytes
por: Barajas-Martinez, Hector, et al.
Publicado: (2020) -
Overlap Arrhythmia Syndromes Resulting from Multiple Genetic Variations Studied in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
por: Treat, Jacqueline A., et al.
Publicado: (2021) -
Cardiotoxicity and Heart Failure: Lessons from Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Anticancer Drugs
por: Sachinidis, Agapios
Publicado: (2020) -
Transcriptional changes associated with advancing stages of heart failure underlie atrial and ventricular arrhythmogenesis
por: Argenziano, Mariana A., et al.
Publicado: (2019) -
Application of the Pluripotent Stem Cells and Genomics in Cardiovascular Research—What We Have Learnt and Not Learnt until Now
por: Simeon, Michael, et al.
Publicado: (2021)