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Self-assembling peptide-based nanoparticles enhance anticancer effect of ellipticine in vitro and in vivo
BACKGROUND AND METHODS: Applications of the anticancer agent, ellipticine, have been limited by its hydrophobicity and toxicity. An efficient delivery system is required to exploit the enormous potential of this compound. Recently, EAK16-II, an ionic-complementary, self-assembling peptide, has been...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396387/ https://www.ncbi.nlm.nih.gov/pubmed/22802684 http://dx.doi.org/10.2147/IJN.S31858 |