The Pro-Inflammatory Cytokine IL-22 Up-Regulates Keratin 17 Expression in Keratinocytes via STAT3 and ERK1/2

BACKGROUND: To investigate the regulation of K17 expression by the pro-inflammatory cytokine IL-22 in keratinocytes and its important role in our previously hypothesized “K17/T cell/cytokine autoimmune loop” in psoriasis. MATERIALS AND METHODS: K17 expression was examined in the IL-22-treated kerati...

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Detalles Bibliográficos
Autores principales: Zhang, Wei, Dang, Erle, Shi, Xiaowei, Jin, Liang, Feng, Zhenzhen, Hu, Lei, Wu, Yan, Wang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396590/
https://www.ncbi.nlm.nih.gov/pubmed/22808266
http://dx.doi.org/10.1371/journal.pone.0040797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396590/
https://www.ncbi.nlm.nih.gov/pubmed/22808266
http://dx.doi.org/10.1371/journal.pone.0040797

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