Cargando…

The Pro-Inflammatory Cytokine IL-22 Up-Regulates Keratin 17 Expression in Keratinocytes via STAT3 and ERK1/2

BACKGROUND: To investigate the regulation of K17 expression by the pro-inflammatory cytokine IL-22 in keratinocytes and its important role in our previously hypothesized “K17/T cell/cytokine autoimmune loop” in psoriasis. MATERIALS AND METHODS: K17 expression was examined in the IL-22-treated kerati...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Wei, Dang, Erle, Shi, Xiaowei, Jin, Liang, Feng, Zhenzhen, Hu, Lei, Wu, Yan, Wang, Gang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396590/ https://www.ncbi.nlm.nih.gov/pubmed/22808266 http://dx.doi.org/10.1371/journal.pone.0040797

Ejemplares similares

Effect of Calcipotriol on IFN-γ-Induced Keratin 17 Expression in Immortalized Human Epidermal Keratinocyte Cells
por: Zhang, Jieyu, et al.
Publicado: (2017)

Keratin 17 Is Required for Lipid Metabolism in Keratinocytes and Benefits Epidermal Permeability Barrier Homeostasis
por: Pang, Bingyu, et al.
Publicado: (2022)

Keratin 17 covalently binds to alpha-enolase and exacerbates proliferation of keratinocytes in psoriasis
por: Luo, Yixin, et al.
Publicado: (2023)

Keratin 17 is Not Always a Marker of Proliferation of Keratinocytes in Skin Diseases
por: Cui, Li, et al.
Publicado: (2021)

Novel key cytokines in allergy: IL-17, IL-22*
por: Eyerich, S., et al.
Publicado: (2017)

Cytokines IL-17 and IL-22 in the host response to infection
por: Valeri, Maria, et al.
Publicado: (2016)

Keratin Promotes Differentiation of Keratinocytes Seeded on Collagen/Keratin Hydrogels
por: Zuniga, Kameel, et al.
Publicado: (2022)

Pivotal Roles of T-Helper 17-Related Cytokines, IL-17, IL-22, and IL-23, in Inflammatory Diseases
por: Qu, Ning, et al.
Publicado: (2013)

Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma
por: Farahani, Rahim, et al.
Publicado: (2014)

Dual Role of Th17 Cytokines, IL-17A,F, and IL-22 in Allergic Asthma
por: Schnyder, Bruno, et al.
Publicado: (2012)

The psoriasis-associated IL-17A induces and cooperates with IL-36 cytokines to control keratinocyte differentiation and function
por: Pfaff, Carolina M., et al.
Publicado: (2017)

Induction of Interleukin-22 (IL-22) production in CD4(+) T Cells by IL-17A Secreted from CpG-Stimulated Keratinocytes
por: Li, Zheng Jun, et al.
Publicado: (2016)

Role of keratin 24 in human epidermal keratinocytes
por: Min, Min, et al.
Publicado: (2017)

Keratin 17 Promotes T Cell Response in Allergic Contact Dermatitis by Upregulating C–C Motif Chemokine Ligand 20
por: Luo, Yixin, et al.
Publicado: (2022)

Renin Promotes STAT4 Phosphorylation to Induce IL-17 Production in Keratinocytes of Oral Lichen Planus
por: Ge, Xuejun, et al.
Publicado: (2020)

Inhibition of Keratinocyte Differentiation by the Synergistic Effect of IL-17A, IL-22, IL-1α, TNFα and Oncostatin M
por: Rabeony, Hanitriniaina, et al.
Publicado: (2014)

Blunted IL17/IL22 and Pro-Inflammatory Cytokine Responses in the Genital Tract and Blood of HIV-Exposed, Seronegative Female Sex Workers in Kenya
por: Chege, Duncan, et al.
Publicado: (2012)

A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4–ERK5 axis
por: Wu, Ling, et al.
Publicado: (2015)

IL-17A Signaling in Colonic Epithelial Cells Inhibits Pro-Inflammatory Cytokine Production by Enhancing the Activity of ERK and PI3K
por: Guo, Xiaoqin, et al.
Publicado: (2014)

Sodium fluoride influences the expression of keratins in cultured keratinocytes
por: Prado, Euridice, et al.
Publicado: (2010)

Inflammation, cytokines, the IL-17/IL-6/STAT3/NF-κB axis, and tumorigenesis
por: Chen, Xiao-Wu, et al.
Publicado: (2015)

IL-17A and IFN-γ Synergistically Induce RNase 7 Expression via STAT3 in Primary Keratinocytes
por: Simanski, Maren, et al.
Publicado: (2013)

Loss of keratinocyte Mcpip1 abruptly activates the IL-23/Th17 and Stat3 pathways in skin inflammation
por: Lichawska-Cieslar, Agata, et al.
Publicado: (2021)

Evaluation of the effects of IL-22 on the proliferation and differentiation of keratinocytes in vitro
por: Zhuang, Le, et al.
Publicado: (2020)

Pro-Inflammatory Signaling by IL-10 and IL-22: Bad Habit Stirred Up by Interferons?
por: Mühl, Heiko
Publicado: (2013)

Alpha-Mangostin: A Potent Inhibitor of TRPV3 and Pro-Inflammatory Cytokine Secretion in Keratinocytes
por: Dang, Thi Huyen, et al.
Publicado: (2023)

Regulation of C-X-C chemokine gene expression by keratin 17 and hnRNP K in skin tumor keratinocytes
por: Chung, Byung Min, et al.
Publicado: (2015)

IL-17 and IL-22 are pivotal cytokines to delay wound healing of S. aureus and P. aeruginosa infected skin
por: Lecron, Jean-Claude, et al.
Publicado: (2022)

Data on pro-inflammatory cytokines IL-1β, IL-17, and IL-6 in the peripheral blood of HIV-infected individuals
por: Saing, Tommy, et al.
Publicado: (2016)

Luteolin-7-glucoside inhibits IL-22/STAT3 pathway, reducing proliferation, acanthosis, and inflammation in keratinocytes and in mouse psoriatic model
por: Palombo, R, et al.
Publicado: (2016)

The IL-17 Family of Cytokines in Psoriasis: IL-17A and Beyond
por: Brembilla, Nicolo Costantino, et al.
Publicado: (2018)

Keratin-dependent regulation of Aire and gene expression in skin tumor keratinocytes
por: Hobbs, Ryan P., et al.
Publicado: (2015)

A role for keratins in supporting mitochondrial organization and function in skin keratinocytes
por: Steen, Kaylee, et al.
Publicado: (2020)

Effect of Gloriosa superba and Catharanthus roseus Extracts on IFN-γ-Induced Keratin 17 Expression in HaCaT Human Keratinocytes
por: Pattarachotanant, Nattaporn, et al.
Publicado: (2014)

The Role of Keratin17 in Human Tumours
por: Zhang, Hanqun, et al.
Publicado: (2022)

MicroRNA-17-3p is upregulated in psoriasis and regulates keratinocyte hyperproliferation and pro-inflammatory cytokine secretion by targeting CTR9
por: Li, Qingwen, et al.
Publicado: (2022)

Inhibition of IL-17 ameliorates keratinocyte-borne cytokine responses in an in vitro model for house-dust-mite triggered atopic dermatitis
por: Haertlé, Juliane, et al.
Publicado: (2023)

IL-22 produced by cancer-associated fibroblasts promotes gastric cancer cell invasion via STAT3 and ERK signaling
por: Fukui, H, et al.
Publicado: (2014)

Monoclonal antibody analysis of keratin expression in epidermal diseases: a 48- and 56-kdalton keratin as molecular markers for hyperproliferative keratinocytes
Publicado: (1984)

IL-17 cytokines in immunity and inflammation
por: Jin, Wei, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_3kojco7r9tjga0u2r1m226f4p9