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Comparative and Evolutionary Analysis of the HES/HEY Gene Family Reveal Exon/Intron Loss and Teleost Specific Duplication Events

BACKGROUND: HES/HEY genes encode a family of basic helix-loop-helix (bHLH) transcription factors with both bHLH and Orange domain. HES/HEY proteins are direct targets of the Notch signaling pathway and play an essential role in developmental decisions, such as the developments of nervous system, som...

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Detalles Bibliográficos
Autores principales: Zhou, Mi, Yan, Jun, Ma, Zhaowu, Zhou, Yang, Abbood, Nibras Najm, Liu, Jianfeng, Su, Li, Jia, Haibo, Guo, An-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396596/
https://www.ncbi.nlm.nih.gov/pubmed/22808219
http://dx.doi.org/10.1371/journal.pone.0040649