PI3Kδ Is Essential for Tumor Clearance Mediated by Cytotoxic T Lymphocytes

BACKGROUND: PI3Kδ is a lipid kinase of the phosphoinositide 3-kinase class 1A family and involved in early signaling events of leukocytes regulating proliferation, differentiation and survival. Currently, several inhibitors of PI3Kδ are under investigation for the treatment of hematopoietic malignan...

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Detalles Bibliográficos
Autores principales: Putz, Eva Maria, Prchal-Murphy, Michaela, Simma, Olivia Annabella, Forster, Florian, Koenig, Xaver, Stockinger, Hannes, Piekorz, Roland P., Freissmuth, Michael, Müller, Mathias, Sexl, Veronika, Zebedin-Brandl, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396622/
https://www.ncbi.nlm.nih.gov/pubmed/22808277
http://dx.doi.org/10.1371/journal.pone.0040852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396622/
https://www.ncbi.nlm.nih.gov/pubmed/22808277
http://dx.doi.org/10.1371/journal.pone.0040852

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