Cargando…
PI3Kδ Is Essential for Tumor Clearance Mediated by Cytotoxic T Lymphocytes
BACKGROUND: PI3Kδ is a lipid kinase of the phosphoinositide 3-kinase class 1A family and involved in early signaling events of leukocytes regulating proliferation, differentiation and survival. Currently, several inhibitors of PI3Kδ are under investigation for the treatment of hematopoietic malignan...
| Autores principales: | , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396622/ https://www.ncbi.nlm.nih.gov/pubmed/22808277 http://dx.doi.org/10.1371/journal.pone.0040852 |