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Redirecting Valvular Myofibroblasts into Dormant Fibroblasts through Light-mediated Reduction in Substrate Modulus

Fibroblasts residing in connective tissues throughout the body are responsible for extracellular matrix (ECM) homeostasis and repair. In response to tissue damage, they activate to become myofibroblasts, which have organized contractile cytoskeletons and produce a myriad of proteins for ECM remodeli...

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Detalles Bibliográficos
Autores principales: Wang, Huan, Haeger, Sarah M., Kloxin, April M., Leinwand, Leslie A., Anseth, Kristi S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396623/
https://www.ncbi.nlm.nih.gov/pubmed/22808079
http://dx.doi.org/10.1371/journal.pone.0039969