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Redirecting Valvular Myofibroblasts into Dormant Fibroblasts through Light-mediated Reduction in Substrate Modulus
Fibroblasts residing in connective tissues throughout the body are responsible for extracellular matrix (ECM) homeostasis and repair. In response to tissue damage, they activate to become myofibroblasts, which have organized contractile cytoskeletons and produce a myriad of proteins for ECM remodeli...
Autores principales: | Wang, Huan, Haeger, Sarah M., Kloxin, April M., Leinwand, Leslie A., Anseth, Kristi S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396623/ https://www.ncbi.nlm.nih.gov/pubmed/22808079 http://dx.doi.org/10.1371/journal.pone.0039969 |
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