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ATRA Inhibits the Proliferation of DU145 Prostate Cancer Cells through Reducing the Methylation Level of HOXB13 Gene
All-trans retinoic acid (ATRA) has been widely investigated for treatments of many cancers including prostate cancer. HOXB13, silenced in androgen receptor-negative (AR(−)) prostate cancer cells, plays a role in AR(−) prostate cancer cell growth arrest. In this study we intended to elucidate the mec...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396626/ https://www.ncbi.nlm.nih.gov/pubmed/22808286 http://dx.doi.org/10.1371/journal.pone.0040943 |