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ATRA Inhibits the Proliferation of DU145 Prostate Cancer Cells through Reducing the Methylation Level of HOXB13 Gene

All-trans retinoic acid (ATRA) has been widely investigated for treatments of many cancers including prostate cancer. HOXB13, silenced in androgen receptor-negative (AR(−)) prostate cancer cells, plays a role in AR(−) prostate cancer cell growth arrest. In this study we intended to elucidate the mec...

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Detalles Bibliográficos
Autores principales: Liu, Zhiwei, Ren, Guoling, Shangguan, Chenyan, Guo, Lijing, Dong, Zhixiong, Li, Yueyang, Zhang, Weina, Zhao, Li, Hou, Pingfu, Zhang, Yu, Wang, Xiuli, Lu, Jun, Huang, Baiqu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396626/
https://www.ncbi.nlm.nih.gov/pubmed/22808286
http://dx.doi.org/10.1371/journal.pone.0040943