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Hepcidin-25 in Chronic Hemodialysis Patients Is Related to Residual Kidney Function and Not to Treatment with Erythropoiesis Stimulating Agents

Hepcidin-25, the bioactive form of hepcidin, is a key regulator of iron homeostasis as it induces internalization and degradation of ferroportin, a cellular iron exporter on enterocytes, macrophages and hepatocytes. Hepcidin levels are increased in chronic hemodialysis (HD) patients, but as of yet,...

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Detalles Bibliográficos
Autores principales: van der Weerd, Neelke C., Grooteman, Muriel P. C., Bots, Michiel L., van den Dorpel, Marinus A., den Hoedt, Claire H., Mazairac, Albert H. A., Nubé, Menso J., Penne, E. Lars, Gaillard, Carlo A., Wetzels, Jack F. M., Wiegerinck, Erwin T., Swinkels, Dorine W., Blankestijn, Peter J., ter Wee, Piet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396629/
https://www.ncbi.nlm.nih.gov/pubmed/22808058
http://dx.doi.org/10.1371/journal.pone.0039783