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Hepcidin-25 in Chronic Hemodialysis Patients Is Related to Residual Kidney Function and Not to Treatment with Erythropoiesis Stimulating Agents
Hepcidin-25, the bioactive form of hepcidin, is a key regulator of iron homeostasis as it induces internalization and degradation of ferroportin, a cellular iron exporter on enterocytes, macrophages and hepatocytes. Hepcidin levels are increased in chronic hemodialysis (HD) patients, but as of yet,...
Autores principales: | van der Weerd, Neelke C., Grooteman, Muriel P. C., Bots, Michiel L., van den Dorpel, Marinus A., den Hoedt, Claire H., Mazairac, Albert H. A., Nubé, Menso J., Penne, E. Lars, Gaillard, Carlo A., Wetzels, Jack F. M., Wiegerinck, Erwin T., Swinkels, Dorine W., Blankestijn, Peter J., ter Wee, Piet M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396629/ https://www.ncbi.nlm.nih.gov/pubmed/22808058 http://dx.doi.org/10.1371/journal.pone.0039783 |
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