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Inhibition of Endoplasmic Reticulum Stress Improves Mouse Embryo Development

X-box binding protein-1 (XBP-1) is an important regulator of a subset of genes during endoplasmic reticulum (ER) stress. In the current study, we analyzed endogenous XBP-1 expression and localization, with a view to determining the effects of ER stress on the developmental competency of preimplantat...

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Detalles Bibliográficos
Autores principales: Zhang, Jin Yu, Diao, Yun Fei, Kim, Hong Rye, Jin, Dong Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396646/
https://www.ncbi.nlm.nih.gov/pubmed/22808162
http://dx.doi.org/10.1371/journal.pone.0040433