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Proteomic Identification of ADAM12 as a Regulator for TGF-β1-Induced Differentiation of Human Mesenchymal Stem Cells to Smooth Muscle Cells

BACKGROUND: Transforming growth factor-β1 (TGF-β1) induces the differentiation of human adipose tissue-derived mesenchymal stem cells (hASCs) into smooth muscle cells. Lipid rafts are cholesterol-rich microdomains in cell membranes that reportedly play a key role in receptor-mediated signal transduc...

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Detalles Bibliográficos
Autores principales: Kim, Young Mi, Kim, Jaeyoon, Heo, Soon Chul, Shin, Sang Hun, Do, Eun Kyoung, Suh, Dong-Soo, Kim, Ki-Hyung, Yoon, Man-Soo, Lee, Taehoon G., Kim, Jae Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396647/
https://www.ncbi.nlm.nih.gov/pubmed/22808268
http://dx.doi.org/10.1371/journal.pone.0040820