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Acute Podocyte Vascular Endothelial Growth Factor (VEGF-A) Knockdown Disrupts alpha(V)beta(3) Integrin Signaling in the Glomerulus
Podocyte or endothelial cell VEGF-A knockout causes thrombotic microangiopathy in adult mice. To study the mechanism involved in acute and local injury caused by low podocyte VEGF-A we developed an inducible, podocyte-specific VEGF-A knockdown mouse, and we generated an immortalized podocyte cell li...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396653/ https://www.ncbi.nlm.nih.gov/pubmed/22808199 http://dx.doi.org/10.1371/journal.pone.0040589 |