A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity

Recombinant adenoviruses are among the most promising tools for vaccine antigen delivery. Recently, the development of new vectors has focused on serotypes to which the human population is less exposed in order to circumvent pre-existing anti vector immunity. This study describes the derivation of a...

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Detalles Bibliográficos
Autores principales: Dicks, Matthew D. J., Spencer, Alexandra J., Edwards, Nick J., Wadell, Göran, Bojang, Kalifa, Gilbert, Sarah C., Hill, Adrian V. S., Cottingham, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396660/
https://www.ncbi.nlm.nih.gov/pubmed/22808149
http://dx.doi.org/10.1371/journal.pone.0040385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396660/
https://www.ncbi.nlm.nih.gov/pubmed/22808149
http://dx.doi.org/10.1371/journal.pone.0040385

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