The Mutational Landscape of Lethal Castrate Resistant Prostate Cancer

Characterization of the prostate cancer transcriptome and genome has identified chromosomal rearrangements and copy number gains/losses, including ETS gene fusions, PTEN loss and androgen receptor (AR) amplification, that drive prostate cancer development and progression to lethal, metastatic castra...

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Detalles Bibliográficos
Autores principales: Grasso, Catherine S., Wu, Yi-Mi, Robinson, Dan R., Cao, Xuhong, Dhanasekaran, Saravana M., Khan, Amjad P., Quist, Michael J., Jing, Xiaojun, Lonigro, Robert J., Brenner, J. Chad, Asangani, Irfan A., Ateeq, Bushra, Chun, Sang Y., Siddiqui, Javed, Sam, Lee, Anstett, Matt, Mehra, Rohit, Prensner, John R., Palanisamy, Nallasivam, Ryslik, Gregory A., Vandin, Fabio, Raphael, Benjamin J., Kunju, Lakshmi P., Rhodes, Daniel R., Pienta, Kenneth J., Chinnaiyan, Arul M., Tomlins, Scott A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396711/
https://www.ncbi.nlm.nih.gov/pubmed/22722839
http://dx.doi.org/10.1038/nature11125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396711/
https://www.ncbi.nlm.nih.gov/pubmed/22722839
http://dx.doi.org/10.1038/nature11125

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