Multi-ethnic Distribution of Clinically Relevant CYP2C Genotypes and Haplotypes

To determine CYP2C19 and CYP2C8 allele frequencies, 28 coding and/or functional variants were genotyped in 1250 African-American, Asian, Caucasian, Hispanic and Ashkenazi Jewish (AJ) individuals. The combined CYP2C19 variant allele frequencies ranged from ~0.30–0.41; however, the CYP2C8 frequencies...

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Detalles Bibliográficos
Autores principales: Martis, Suparna, Peter, Inga, Hulot, Jean-Sébastien, Kornreich, Ruth, Desnick, Robert J., Scott, Stuart A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396745/
https://www.ncbi.nlm.nih.gov/pubmed/22491019
http://dx.doi.org/10.1038/tpj.2012.10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396745/
https://www.ncbi.nlm.nih.gov/pubmed/22491019
http://dx.doi.org/10.1038/tpj.2012.10

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