IL-6 triggers IL-21 production by human CD4(+) T cells to drive STAT3-dependent plasma cell differentiation in B cells

Interleukin (IL)-21-producing CD4(+) T cells are central to humoral immunity. Deciphering the signals that induce IL-21 production in CD4(+) T cells and those triggered by IL-21 in B cells are, therefore, of importance for understanding the generation of antibody responses. Here, we show that IL-6 i...

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Detalles Bibliográficos
Autores principales: Diehl, Sean A., Schmidlin, Heike, Nagasawa, Maho, Blom, Bianca, Spits, Hergen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396759/
https://www.ncbi.nlm.nih.gov/pubmed/22491065
http://dx.doi.org/10.1038/icb.2012.17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396759/
https://www.ncbi.nlm.nih.gov/pubmed/22491065
http://dx.doi.org/10.1038/icb.2012.17

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