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Genetic and Epigenetic Regulation of the Organic Cation Transporter 3, SLC22A3

Human organic cation transporter 3 (OCT3, SLC22A3) mediates the uptake of many important endogenous amines and basic drugs in a variety of tissues. OCT3 is identified as one of the important risk loci for prostate cancer and is markedly under-expressed in aggressive prostate cancers. The goal of thi...

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Detalles Bibliográficos
Autores principales: Chen, Ligong, Hong, Chibo, Chen, Eugene C., Yee, Sook Wah, Xu, Lu, Almof, Emil U., Wen, Christopher, Fujii, Kacyn, Johns, Susan J., Stryke, Doug, Ferrin, Thomas E., Simko, Jeff, Chen, Xin, Costello, Joseph F., Giacomini, Kathleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396779/
https://www.ncbi.nlm.nih.gov/pubmed/22231567
http://dx.doi.org/10.1038/tpj.2011.60