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A Novel Role for Bcl-2 in Regulation of Cellular Calcium Extrusion

The antiapoptotic protein Bcl-2 [1, 2] plays important roles in Ca(2+) signaling [3] by influencing inositol triphosphate receptors and regulating Ca(2+)-induced Ca(2+) release [4–6]. Here we investigated whether Bcl-2 affects Ca(2+) extrusion in pancreatic acinar cells. We specifically blocked the...

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Detalles Bibliográficos
Autores principales: Ferdek, Pawel E., Gerasimenko, Julia V., Peng, Shuang, Tepikin, Alexei V., Petersen, Ole H., Gerasimenko, Oleg V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3396842/
https://www.ncbi.nlm.nih.gov/pubmed/22704985
http://dx.doi.org/10.1016/j.cub.2012.05.002