Design, synthesis and biological activity of new neurohypophyseal hormones analogues conformationally restricted in the N-terminal part of the molecule. Highly potent OT receptor antagonists

In this study we present the synthesis and some pharmacological properties of fourteen new analogues of neurohypophyseal hormones conformationally restricted in the N-terminal part of the molecule. All new peptides were substituted at position 2 with cis-1-amino-4-phenylcyclohexane-1-carboxylic acid...

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Detalles Bibliográficos
Autores principales: Kwiatkowska, Anna, Ptach, Monika, Borovičková, Lenka, Slaninová, Jiřina, Lammek, Bernard, Prahl, Adam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397136/
https://www.ncbi.nlm.nih.gov/pubmed/22038179
http://dx.doi.org/10.1007/s00726-011-1109-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397136/
https://www.ncbi.nlm.nih.gov/pubmed/22038179
http://dx.doi.org/10.1007/s00726-011-1109-6

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