Comparison of SARS and NL63 Papain-Like Protease Binding Sites and Binding Site Dynamics: Inhibitor Design Implications

The human severe acute respiratory syndrome coronavirus (SARS-CoV) and the NL63 coronaviruses are human respiratory pathogens for which no effective antiviral treatment exists. The papain-like cysteine proteases encoded by the coronavirus (SARS-CoV: PLpro; NL63: PLP1 and PLP2) represent potential ta...

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Detalles Bibliográficos
Autores principales: Chaudhuri, Rima, Tang, Sishi, Zhao, Guijun, Lu, Hui, Case, David A., Johnson, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397151/
https://www.ncbi.nlm.nih.gov/pubmed/22004941
http://dx.doi.org/10.1016/j.jmb.2011.09.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397151/
https://www.ncbi.nlm.nih.gov/pubmed/22004941
http://dx.doi.org/10.1016/j.jmb.2011.09.030

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