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Comparison of SARS and NL63 Papain-Like Protease Binding Sites and Binding Site Dynamics: Inhibitor Design Implications
The human severe acute respiratory syndrome coronavirus (SARS-CoV) and the NL63 coronaviruses are human respiratory pathogens for which no effective antiviral treatment exists. The papain-like cysteine proteases encoded by the coronavirus (SARS-CoV: PLpro; NL63: PLP1 and PLP2) represent potential ta...
Autores principales: | Chaudhuri, Rima, Tang, Sishi, Zhao, Guijun, Lu, Hui, Case, David A., Johnson, Michael E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397151/ https://www.ncbi.nlm.nih.gov/pubmed/22004941 http://dx.doi.org/10.1016/j.jmb.2011.09.030 |
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