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Inactivation of GPR30 reduces growth of triple-negative breast cancer cells: possible application in targeted therapy

Triple-negative breast cancers lack estrogen receptor α (ERα), progesterone receptor, and do not overexpress human epidermal growth factor receptor 2 (Her-2). They are neither susceptible to endocrine therapy nor to a therapy using the anti-Her-2 antibody, trastuzumab. Therefore, an efficient target...

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Detalles Bibliográficos
Autores principales: Girgert, Rainer, Emons, Günter, Gründker, Carsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397221/
https://www.ncbi.nlm.nih.gov/pubmed/22290080
http://dx.doi.org/10.1007/s10549-012-1968-x