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Mechanisms of Coronavirus Cell Entry Mediated by the Viral Spike Protein

Coronaviruses are enveloped positive-stranded RNA viruses that replicate in the cytoplasm. To deliver their nucleocapsid into the host cell, they rely on the fusion of their envelope with the host cell membrane. The spike glycoprotein (S) mediates virus entry and is a primary determinant of cell tro...

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Detalles Bibliográficos
Autores principales: Belouzard, Sandrine, Millet, Jean K., Licitra, Beth N., Whittaker, Gary R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397359/
https://www.ncbi.nlm.nih.gov/pubmed/22816037
http://dx.doi.org/10.3390/v4061011