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Anhedonia requires MC4 receptor-mediated synaptic adaptations in nucleus accumbens

Chronic stress is a strong diathesis for depression in humans and is used to generate animal models of depression. It commonly leads to several major symptoms of depression including dysregulated feeding behavior, anhedonia, and behavioral despair. Although hypotheses defining the neural pathophysio...

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Detalles Bibliográficos
Autores principales: Lim, Byung Kook, Huang, Kee Wui, Grueter, Brad A., Rothwell, Patrick E., Malenka, Robert C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397405/
https://www.ncbi.nlm.nih.gov/pubmed/22785313
http://dx.doi.org/10.1038/nature11160