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“Scanning mutagenesis” of the amino acid sequences flanking phosphorylation site 1 of the mitochondrial pyruvate dehydrogenase complex

The mitochondrial pyruvate dehydrogenase complex (mtPDC) is regulated by reversible seryl-phosphorylation of the E1α subunit by a dedicated, intrinsic kinase. The phospho-complex is reactivated when dephosphorylated by an intrinsic PP2C-type protein phosphatase. Both the position of the phosphorylat...

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Detalles Bibliográficos
Autores principales: Ahsan, Nagib, Swatek, Kirby N., Zhang, Jingfen, Miernyk, Ján A., Xu, Dong, Thelen, Jay J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397410/
https://www.ncbi.nlm.nih.gov/pubmed/22811682
http://dx.doi.org/10.3389/fpls.2012.00153