Mycalamide A Shows Cytotoxic Properties and Prevents EGF-Induced Neoplastic Transformation through Inhibition of Nuclear Factors

Mycalamide A, a marine natural compound previously isolated from sponges, is known as a protein synthesis inhibitor with potent antitumor activity. However, the ability of this compound to prevent malignant transformation of cells has never been examined before. Here, for the first time, we report t...

Descripción completa

Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Fedorov, Sergey N., Kalinovsky, Anatoly I., Shubina, Larisa K., Bokemeyer, Carsten, Stonik, Valentin A., Honecker, Friedemann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397435/
https://www.ncbi.nlm.nih.gov/pubmed/22822368
http://dx.doi.org/10.3390/md10061212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397435/
https://www.ncbi.nlm.nih.gov/pubmed/22822368
http://dx.doi.org/10.3390/md10061212

Ejemplares similares