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By-Passing Large Screening Experiments Using Sequencing as a Tool to Identify scFv Fragments Targeting Atherosclerotic Lesions in a Novel In Vivo Phage Display Selection

Atherosclerosis is a chronic, progressive inflammatory disease that may develop into vulnerable lesions leading to thrombosis. To interrogate the molecular components involved in this process, single-chain variable fragments (scFvs) from a semi-synthetic human antibody library were selected on the l...

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Detalles Bibliográficos
Autores principales: Deramchia, Kamel, Jacobin-Valat, Marie-Josee, Laroche-Traineau, Jeanny, Bonetto, Stephane, Sanchez, Stephane, Dos Santos, Pierre, Massot, Philippe, Franconi, Jean-Michel, Martineau, Pierre, Clofent-Sanchez, Gisele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397503/
https://www.ncbi.nlm.nih.gov/pubmed/22837671
http://dx.doi.org/10.3390/ijms13066902