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Toward the Prediction of FBPase Inhibitory Activity Using Chemoinformatic Methods

Currently, Chemoinformatic methods are used to perform the prediction for FBPase inhibitory activity. A genetic algorithm-random forest coupled method (GA-RF) was proposed to predict fructose 1,6-bisphosphatase (FBPase) inhibitors to treat type 2 diabetes mellitus using the Mold(2) molecular descrip...

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Detalles Bibliográficos
Autores principales: Hao, Ming, Zhang, Shuwei, Qiu, Jieshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397509/
https://www.ncbi.nlm.nih.gov/pubmed/22837677
http://dx.doi.org/10.3390/ijms13067015