A Computational Study on Thiourea Analogs as Potent MK-2 Inhibitors

Mitogen-activated protein kinase-activated protein kinase 2 (MK-2) has been identified as a drug target for the treatment of inflammatory diseases. Currently, a series of thiourea analogs as potent MK-2 inhibitors were studied using comprehensive computational methods by 3D-QSAR, molecular docking a...

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Detalles Bibliográficos
Autores principales: Hao, Ming, Ren, Hong, Luo, Fang, Zhang, Shuwei, Qiu, Jieshan, Ji, Mingjuan, Si, Hongzong, Li, Guohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397511/
https://www.ncbi.nlm.nih.gov/pubmed/22837679
http://dx.doi.org/10.3390/ijms13067057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397511/
https://www.ncbi.nlm.nih.gov/pubmed/22837679
http://dx.doi.org/10.3390/ijms13067057

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