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Oral Administration of Apigenin Inhibits Metastasis through AKT/P70S6K1/MMP-9 Pathway in Orthotopic Ovarian Tumor Model

Apigenin, a flavonoid commonly present in the daily diet, is known for its potential anti-tumor properties. However, the effect of apigenin via oral administration on tumor growth and metastasis remains unknown. In this study we developed an orthotopic ovarian tumor model in nude mice to test the ef...

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Detalles Bibliográficos
Autores principales: He, Jun, Xu, Qing, Wang, Min, Li, Chongyong, Qian, Xu, Shi, Zhumei, Liu, Ling-Zhi, Jiang, Bing-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397525/
https://www.ncbi.nlm.nih.gov/pubmed/22837693
http://dx.doi.org/10.3390/ijms13067271