Looping Mediated Interaction between the Promoter and 3′ UTR Regulates Type II Collagen Expression in Chondrocytes

Type II collagen is the major component of articular cartilage and is mainly synthesized by chondrocytes. Repeated sub-culturing of primary chondrocytes leads to reduction of type II collagen gene (Col2a1) expression, which mimics the process of chondrocyte dedifferentiation. Although the functional...

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Detalles Bibliográficos
Autores principales: Jash, Arijita, Yun, Kangsun, Sahoo, Anupama, So, Jae-Seon, Im, Sin-Hyeog
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397959/
https://www.ncbi.nlm.nih.gov/pubmed/22815835
http://dx.doi.org/10.1371/journal.pone.0040828

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397959/
https://www.ncbi.nlm.nih.gov/pubmed/22815835
http://dx.doi.org/10.1371/journal.pone.0040828

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