Rosiglitazone Improves Survival and Hastens Recovery from Pancreatic Inflammation in Obese Mice

Obesity increases severity of acute pancreatitis (AP) by unclear mechanisms. We investigated the effect of the PPAR-gamma agonist rosiglitazone (RGZ, 0.01% in the diet) on severity of AP induced by administration of IL-12+ IL-18 in male C57BL6 mice fed a low fat (LFD) or high fat diet (HFD), under t...

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Detalles Bibliográficos
Autores principales: Pini, Maria, Rhodes, Davina H., Castellanos, Karla J., Cabay, Robert J., Grady, Eileen F., Fantuzzi, Giamila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397967/
https://www.ncbi.nlm.nih.gov/pubmed/22815875
http://dx.doi.org/10.1371/journal.pone.0040944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397967/
https://www.ncbi.nlm.nih.gov/pubmed/22815875
http://dx.doi.org/10.1371/journal.pone.0040944

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