Staphylococcus aureus Isolates Encode Variant Staphylococcal Enterotoxin B Proteins That Are Diverse in Superantigenicity and Lethality

Staphylococcus aureus produces superantigens (SAgs) that bind and cross-link T cells and APCs, leading to activation and proliferation of immune cells. SAgs bind to variable regions of the β-chains of T cell receptors (Vβ-TCRs), and each SAg binds a unique subset of Vβ-TCRs. This binding leads to ma...

Descripción completa

Detalles Bibliográficos
Autores principales: Kohler, Petra L., Greenwood, Seth D., Nookala, Suba, Kotb, Malak, Kranz, David M., Schlievert, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397982/
https://www.ncbi.nlm.nih.gov/pubmed/22815951
http://dx.doi.org/10.1371/journal.pone.0041157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397982/
https://www.ncbi.nlm.nih.gov/pubmed/22815951
http://dx.doi.org/10.1371/journal.pone.0041157

Ejemplares similares