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Staphylococcus aureus Isolates Encode Variant Staphylococcal Enterotoxin B Proteins That Are Diverse in Superantigenicity and Lethality

Staphylococcus aureus produces superantigens (SAgs) that bind and cross-link T cells and APCs, leading to activation and proliferation of immune cells. SAgs bind to variable regions of the β-chains of T cell receptors (Vβ-TCRs), and each SAg binds a unique subset of Vβ-TCRs. This binding leads to ma...

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Detalles Bibliográficos
Autores principales:	Kohler, Petra L., Greenwood, Seth D., Nookala, Suba, Kotb, Malak, Kranz, David M., Schlievert, Patrick M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397982/ https://www.ncbi.nlm.nih.gov/pubmed/22815951 http://dx.doi.org/10.1371/journal.pone.0041157

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