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IRF7 Regulates TLR2-Mediated Activation of Splenic CD11c(hi) Dendritic Cells

Members of the Interferon Regulatory Factor (IRF) family of transcription factors play an essential role in the development and function of the immune system. Here we investigated the role of IRF7 in the functional activation of conventional CD11c(hi) splenic dendritic cells (cDCs) in vitro and in v...

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Detalles Bibliográficos
Autores principales: Owens, Benjamin M. J., Moore, John W. J., Kaye, Paul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398003/
https://www.ncbi.nlm.nih.gov/pubmed/22815909
http://dx.doi.org/10.1371/journal.pone.0041050