Systems Biological Approach of Molecular Descriptors Connectivity: Optimal Descriptors for Oral Bioavailability Prediction

BACKGROUND: Poor oral bioavailability is an important parameter accounting for the failure of the drug candidates. Approximately, 50% of developing drugs fail because of unfavorable oral bioavailability. In silico prediction of oral bioavailability (%F) based on physiochemical properties are highly...

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Detalles Bibliográficos
Autores principales: Ahmed, Shiek S. S. J., Ramakrishnan, V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398012/
https://www.ncbi.nlm.nih.gov/pubmed/22815781
http://dx.doi.org/10.1371/journal.pone.0040654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398012/
https://www.ncbi.nlm.nih.gov/pubmed/22815781
http://dx.doi.org/10.1371/journal.pone.0040654

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