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Statins Affect the Presentation of Endothelial Chemokines by Targeting to Multivesicular Bodies

BACKGROUND: In addition to lowering cholesterol, statins are thought to beneficially modulate inflammation. Several chemokines including CXCL1/growth-related oncogene (GRO)-α, CXCL8/interleukin (IL)-8 and CCL2/monocyte chemoattractant protein (MCP)-1 are important in the pathogenesis of atherosclero...

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Detalles Bibliográficos
Autores principales: Hol, Johanna, Otterdal, Kari, Breland, Unni M., Stang, Espen, Pedersen, Turid M., Hagelsteen, Kathrine, Ranheim, Trine, Kasprzycka, Monika, Halvorsen, Bente, Haraldsen, Guttorm, Aukrust, Pål
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398041/
https://www.ncbi.nlm.nih.gov/pubmed/22815786
http://dx.doi.org/10.1371/journal.pone.0040673