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Effects of hypoxia inducible factors-1α on autophagy and invasion of trophoblasts

OBJECTIVE: This study was undertaken to determine the effect of hypoxia inducible factor (HIF)-1α on the cell death, autophagy, and invasion of trophoblasts. METHODS: To understand the effect of HIF-1α, we inhibited HIF-1α using siRNA under normoxia and hypoxia conditions. Invasion assay and zymogra...

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Detalles Bibliográficos
Autores principales: Choi, Jong-Ho, Lee, Hyun-Jung, Yang, Tae-Hyun, Kim, Gi Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Reproductive Medicine 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398120/
https://www.ncbi.nlm.nih.gov/pubmed/22816073
http://dx.doi.org/10.5653/cerm.2012.39.2.73