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From tumor hypoxia to cancer progression: the implications of hypoxia-inducible factor-1 expression in cancers
Hypoxia, defined as a decrease of tissue oxygen levels, represents a fundamental pathophysiological condition in the microenvironment of solid tumors. Tumor hypoxia is known to be associated with radio/chemo-resistance and metastasis that eventually lead to cancer progression contributing to poor pr...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Association of Anatomists
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398177/ https://www.ncbi.nlm.nih.gov/pubmed/22822460 http://dx.doi.org/10.5115/acb.2012.45.2.73 |