Germline Melanocortin-1-Receptor Genotype Is Associated with Severity of Cutaneous Phenotype in Congenital Melanocytic Nevi: A Role for MC1R in Human Fetal Development

Congenital melanocytic nevi (CMN) are pigmented birthmarks that affect up to 80% of the skin surface area. The increased frequency of CMN in families of severely affected individuals is suggestive of a predisposing germline genotype. We noted a high prevalence of red hair in affected families, and c...

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Detalles Bibliográficos
Autores principales: Kinsler, Veronica A, Abu-Amero, Sayeda, Budd, Peter, Jackson, Ian J, Ring, Susan M, Northstone, Kate, Atherton, David J, Bulstrode, Neil W, Stanier, Philip, Hennekam, Raoul C, Sebire, Neil J, Moore, Gudrun E, Healy, Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398254/
https://www.ncbi.nlm.nih.gov/pubmed/22572819
http://dx.doi.org/10.1038/jid.2012.95

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3398254/
https://www.ncbi.nlm.nih.gov/pubmed/22572819
http://dx.doi.org/10.1038/jid.2012.95

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